What is Human Papilloma Virus (HPV)?

人乳头状瘤病毒(HPV)感染是生殖道最常见的病毒性感染，绝大多数HPV感染无症状或不引起疾病，且约90%会在2年之内消退，但高危HPV基因型的持续感染可能导致包括癌前病变在内的一系列疾病。

宫颈癌是女性最常见恶性肿瘤之一，几乎所有宫颈癌病例都可以追溯到人乳头状瘤病毒感染。因此，子宫颈癌是与HPV直接相关的常见疾病。感染特定类型的HPV还可能会导致直肠癌、外阴癌、阴道癌、阴茎癌和口咽癌等。

特定类型的HPV（特别是6型和11型）还可能引发生殖器疣和呼吸道乳头状瘤病。

Human papillomavirus (HPV) infection is the most common viral infection in the reproductive tract. The vast majority of HPV infection is asymptomatic or does not cause disease, and about 90% will subside within 2 years. However, the continuous infection of high-risk HPV genotypes may lead to a series of diseases, including precancerous lesions.

Cervical cancer is one of the most common malignant tumors in women. Almost all cases of cervical cancer can be traced back to human papillomavirus infection. Hence, cervical cancer is a common disease directly related to HPV. Infection with specific types of HPV may also lead to rectal cancer, vulvar cancer, vaginal cancer, penile cancer and oropharyngeal cancer.

Certain types of HPV (especially types 6 and 11) may also cause genital warts and respiratory papillomatosis.

How does HPV cause cervical cancer?

HPV感染女性均面临癌前病变逐步发展为浸润性宫颈癌的风险。约70%的宫颈癌与16型HPV和18型HPV感染有关，约90%的肛门和生殖器疣与6型HPV和11型HPV有关。

免疫系统正常的妇女，HPV感染发展为宫颈癌需要15到20年的时间。免疫系统薄弱的妇女，例如感染艾滋病毒但未治疗者，则只需要5至10年时间; HPV持续存在是宫颈癌的高危因素。

HPV infected women are at risk of developing precancerous lesions into invasive cervical cancer. About 70% of cervical cancer is associated with HPV 16 and HPV 18 infection, and about 90% of anal and genital warts are associated with HPV 6 and HPV 11.

Women who are immunocompetent may take 15 to 20 years for HPV infection to develop into cervical cancer. Women with impaired immunity, such as those with acquired immunodeficiency syndrome (AIDS), may only take 5 to 10 years; HPV infections remain as a high risk factor for cervical cancer.

 How to prevent HPV?

最有效的预防方式：

疫苗接种 + 筛查 + 治疗 = 消灭HPV

Most effective way of prevention: 

Vaccination + Screening + Treatment = Eliminate HPV

Who are not suitable to be vaccinated?

•对疫苗所含任何成分严重过敏反应者禁用；任何严重过敏，包括对酵母或乳胶过敏

•孕期和哺乳期女士不推荐接种HPV疫苗

•Not recommended for those with severe allergic reaction to any component contained in the vaccine; any serious allergies, including allergies to yeast or latex

•Pregnant and lactating women are not recommended to receive HPV vaccine

Types of HPV vaccines & age suitability

好不容易等待到内地HPV 9 价疫苗年龄已扩龄至9~45岁；但目前在内地无论是HPV 4 价或HPV 9 价疫苗接种都需提前预约，等待时间最短的需要几个月，长的甚至需等待1-2年时间。

不愿意等待的，有什么其他方法能快速接种上HPV 9 价疫苗？

莱佛士医疗集团（香港）在中环和国际机场设有诊所皆可提供男女客户接种HPV 9 价疫苗；有兴趣了解更多可扫以下二维码。

The suitability age to receive HPV 9 vaccines in Chinese Mainland is now available for 9~45 years old. However, in Chinese Mainland both HPV 4 & HPV 9 vaccines require advance appointment and usually the waiting time ranges from several months to 1-2 years.

For those who do not wish to wait, is there any other alternative to get vaccinated with HPV 9 vaccines?

Raffles Medical Group (Hong Kong) has clinics in Central and International Airport that provides HPV 9 vaccinations for both male and female clients, scan the QR code below to find out more.